MECHANISM OF ACTION OF PENICILLIN

Mechanism of action of penicillin.

Cytochemical Interpretation of the Mechanism of Penicillin Action.

According to current usage, the term antibiotic designates a product of the metabolism of one micro6rganism that is antagonistic to the continuation of the normal life activities of another micro6rganism when present even in very low concentrations. Since the early literature on antibiosis has been covered extensively (4, 7, 29, 70, 71, 145, 190), we shall dispense with this phase of the subjec...

The Mechanism of Action of Penicillin PENICILLIN ACYLATES THE ACTIVE SITE OF BACILLUS STEAROTHERMOPHZLUS

Penicillin kills susceptible bacteria by specifically inhibiting the transpeptidase that catalyzes the final step in cell wall biosynthesis, the cross-linking of peptidoglycan. It was hypothesized (Tipper, D., and Strominger, J. (1965) Proc. Natl. Acad. Sei. U. S. A. 64,11331141) that 1) penicillin is a structural analog of the acylD-alanyl-D-alanine terminus of the pentapeptide side chains of ...

Mechanism of Action of the Thyroid Hormone on the Heart

SUMMARY  The foliowing cardiac effects may be at­tributed to thyroxin:  1-Thyroxin augments all anaerobic pro­cesses in the body includ::ng the heart, and decreases the glycogen content of the heart ( 1, 2, 5, 27). The resistance of the heart to anoxia is increased in hyperthyroidism ( 25). 2- Thyroxin influences the cardiac weight and prevents cardiac atrophy (3, 8, 10, 11, 19, 20, 21, 30...

Antibacterial Activity of Polypyrrole-Chitosan Nanocomposite: Mechanism of Action

Polypyrrole-chitosan nanocomposite (PPy-CTN) was synthesized by dispersion polymerization of PPy in presence of CTN. Preparation of spherical PPy nanoparticles that were successfully covered with a thin layer of chitosan was confirm by transmission electron microscopy (TEM) technique. Characterization techniques also revealed the presence of CNT in the polymer matrix and its presence was confir...